Turn on merging of Perl*Handler arrays. For example, with this setting:

PerlFixupHandler Apache::FixupA

<Location /inside>
    PerlFixupHandler Apache::FixupB
</Location>

a request for /inside runs only Apache::FixupB (mod_perl 1.0 behavior). But with this configuration:

PerlFixupHandler Apache::FixupA

<Location /inside>
    PerlOptions +MergeHandlers
    PerlFixupHandler Apache::FixupB
</Location>

a request for /inside will run both the Apache::FixupA and Apache::FixupB handlers.